The player controls Lana, the woman escorting Amy and protecting her as the two attempt to escape their disease-ridden town. They encounter monsters and the military, among other foes, in their attempt to escape. The player is forced to protect Amy from the zombies, often making her hide, to avoid detection. However, Lana starts succumbing to the plague without medicine, and thus must remain close to Amy, to return for healing. There are syringes infrequently, which allow Lana to heal without returning to Amy. However, when Lana is somewhat infected, she can safely walk past zombies, which necessitates a balance between healing and zombification. At certain times, Lana must rely on Amy for other abilities: Amy can use shockwaves, to push enemies and objects, causing distractions, as well as a sound bubble, muffling glass either being smashed or stepped on, defending Lana. Amy also hacks computers and climbs through vents when Lana needs her to.